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Table 5 Annotated urine-based bladder cancer associated diagnostic

From: Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature

Full name Abbreviation Ascribed function Location Interacts with other members of signature
Interleukin 8 IL8 chemoattractant & angiogenesis Extracellular MMP9, SDC1
Angiogenin ANG angiogenesis Extracellular, nucleus None
Vascular endothelial growth factor A VEGFA angiogenesis Extracellular, cytoplasm None
Matrix metallopeptidase 9 MMP9 breakdown of extracellular matrix Extracellular IL8, MMP10
Matrix metallopeptidase 10 MMP10 breakdown of extracellular matrix Extracellular MMP9
Serpin peptidase inhibitor SERPINA1 serine protease inhibitor Extracellular None
Serpin peptidase inhibitor SERPINE1 serine endopeptidase inhibitor Extracellular, plasma membrane None
Carbonic anhydrase IX CA9 catalyze the reversible hydration of carbon dioxide Plasma membrane None
Apolipoprotein E APOE Lipoprotein catabolism and metabolism Extracellular, plasma membrane, cytoplasm None
Syndecan 1 SDC1 cell binding, cell signaling, cytoskeletal organization Plasma membrane, cytoplasm IL8