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Table 5 Annotated urine-based bladder cancer associated diagnostic

From: Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature

Full name

Abbreviation

Ascribed function

Location

Interacts with other members of signature

Interleukin 8

IL8

chemoattractant & angiogenesis

Extracellular

MMP9, SDC1

Angiogenin

ANG

angiogenesis

Extracellular, nucleus

None

Vascular endothelial growth factor A

VEGFA

angiogenesis

Extracellular, cytoplasm

None

Matrix metallopeptidase 9

MMP9

breakdown of extracellular matrix

Extracellular

IL8, MMP10

Matrix metallopeptidase 10

MMP10

breakdown of extracellular matrix

Extracellular

MMP9

Serpin peptidase inhibitor

SERPINA1

serine protease inhibitor

Extracellular

None

Serpin peptidase inhibitor

SERPINE1

serine endopeptidase inhibitor

Extracellular, plasma membrane

None

Carbonic anhydrase IX

CA9

catalyze the reversible hydration of carbon dioxide

Plasma membrane

None

Apolipoprotein E

APOE

Lipoprotein catabolism and metabolism

Extracellular, plasma membrane, cytoplasm

None

Syndecan 1

SDC1

cell binding, cell signaling, cytoskeletal organization

Plasma membrane, cytoplasm

IL8