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Figure 1 | Diagnostic Pathology

Figure 1

From: Medullary colon cancer presenting with total necrosis of all regional lymph node metastases: morphologic description of a presumed immune-mediated event

Figure 1

Histology of the primary tumor. a) The well-circumscribed primary medullary carcinoma is on the left (arrows). The caecal muscular wall (right) shows a marked Crohn's-like inflammatory infiltrate. b and c) Tumor cells are arranged in cords with associated intra-tumoral lymphocytes. Gland formation is absent. There are high-grade cytologic features and several mitoses. Necrosis is absent. d) Pancytokeratin positivity of the tumor cells. Normal colonic epithelium at bottom right provides a positive internal control.

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Diagnostic Pathology

ISSN: 1746-1596

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