Table 2 Association of the combined aberrant expression of NDRG2 and CD24 proteins with clinicopathological characteristics of 130 patients with hepatocellular carcinoma
Clinicopathological characteristics | Case | NDRG2-low/CD24-high (n, %) | P |
|---|---|---|---|
Age (years) | Â | Â | Â |
≤50 | 72 | 28 (38.89) | NS |
>50 | 58 | 22 (37.93) | |
Gender | Â | Â | Â |
Male | 96 | 35 (36.46) | NS |
Female | 34 | 15 (44.12) | |
Serum AFP | Â | Â | Â |
Positive | 72 | 34 (47.22) | 0.03 |
Negative | 58 | 16 (27.59) | |
Tumor stage | Â | Â | Â |
T1 | 23 | 0 (0) | 0.001 |
T2 | 40 | 10 (25.00) | |
T3 | 52 | 25 (48.08) | |
T4 | 15 | 15 (100.00) | |
Tumor grade | Â | Â | Â |
G1 | 31 | 5 (16.13) | 0.02 |
G2 | 76 | 30 (39.47) | |
G3 | 23 | 15 (65.22) | |
Growth pattern | Â | Â | Â |
Trabecular | 101 | 40 (39.60) | NS |
Nontrabecular | 29 | 10 (34.48) | |
Cirrhosis | Â | Â | Â |
Yes | 86 | 35 (40.70) | NS |
No | 44 | 15 (34.09) | |
Underlying liver disease | Â | Â | Â |
Alcoholic | 25 | 10 (40.00) | NS |
Hepatitis B | 49 | 20 (40.82) | |
Hepatitis C | 35 | 10 (28.57) | |
Unknown | 21 | 10 (47.62) |