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Table 4 The immunoreactive score (IRS)

From: Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue – a review

A (percentage of positive cells) B (intensity of staining) IRS score (multiplication of A and B)
0 = no positive cells 0 = no color reaction 0-1 = negative
1 = <10% of positive cells 1 = mild reaction 2-3 = mild
2 = 10-50% positive cells 2 = moderate reaction 4-8 = moderate
3 = 51-80% positive cells 3 = intense reaction 9-12 = strongly positive
4 = >80% positive cells Final IRS score (A × B): 0-12