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Table 4 The immunoreactive score (IRS)

From: Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue – a review

A (percentage of positive cells)

B (intensity of staining)

IRS score (multiplication of A and B)

0 = no positive cells

0 = no color reaction

0-1 = negative

1 = <10% of positive cells

1 = mild reaction

2-3 = mild

2 = 10-50% positive cells

2 = moderate reaction

4-8 = moderate

3 = 51-80% positive cells

3 = intense reaction

9-12 = strongly positive

4 = >80% positive cells

Final IRS score (A × B): 0-12