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Table 3 Results translocation analysis, mitotic index and immunohistochemical staining

From: Solitary fibrous tumor – clinicopathologic, immunohistochemical and molecular analysis of 28 cases

Case Fusion mit. CD34 CD99 EMA SMA S100 BCL2 STAT6 EGR1 Others
1 Ex4-Ex3 8/10 + + - - - + + 1 desmine -
2 Positive 3/10 + +   + + + + 3 desmine -, CK-pan -
3 Ex4-Ex3 3/10 +    -   + + 1 desmine -
4 Negative 0/10 - + - + - + + 1 desmine -
5 Ex4-Ex3 0/10 + +   - - + + 1 desmine -, CK-pan -
6 Ex4-Ex3 4/10 + w+    - + + 2 CK-pan +
7 Negative 1/10 + + - - - + + 5 CK-pan -
8 Positive 0/10 + +   -   + + 2 CK-pan -
9 Ex7-Ex3 0/10 + +     + + 2 CK-pan -
10 Negative 1/10 + + - - - + + 3 desmine -, CK-pan -
11 Negative 0/10 + +   - - + + 2 desmine -, CK-pan -
12 Ex4-Ex3 1/10 +      + + 4 desmine -
13 Negative 0/10 + + f+ - - + + 3 desmine -
14 Ex4-Ex3 0/10 + +     + + 1  
15 Ex4-Ex3 0/10 + +   - - w+ + NA  
16 Ex6-Ex17 30/10 + +     + + 3 desmine -
17 Ex6-Ex18 13/10 + + -   - + + 1 desmine -, CK-pan -
18 Ex4-Ex3 0/10 +    - - + + 2 desmine f+, CK-pan -
19 Ex4-Ex3 0/10 +    - -   + 1 desmine -
20 Negative 1/10 +    - -   + 1 desmine -, CK-pan -
21 Ex6-Ex18 0/10 +      + + 1  
22 Ex6-Ex3 0/10 +    w+ -   + 1 desmine -
23 Ex4-Ex3 8/10 + +   - - + + 1 desmine -
24 Negative 1/10 + +     + + 3 desmine -, CK-pan -
25 Ex4-Ex3 1/10 +       + 1  
26 NA 0/10 +       + 5  
27 Ex6-Ex18 0/10 +       + 2  
28 NA 6/10 + -    -   + 5 desmine -, CK-pan -
  1. Mit., mitotic figures/10 HPF; w+, weakly positive; f+, focally positive; NA = not assessable EGR1: 0 = negative; 1 = <5% nuclei +; 2 = 5-25% nuclei +; 3 = 26-50% nuclei +; 4 = 51-75% nuclei +; 5 = 76-100% nuclei +.
  2. Fusion-positive cases are characterized by exon junctions, except for case 8 showing a complex junction indicated as positive; negative, no fusion detected.