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Table 1 Brief summary of cases reported in the literature of scrotal IgG4 related pseudotumor

From: IgG4-related disease of the paratestis in a patient with Wells syndrome: a case report

No. Reference Era Age Presentation Diagnosis and multiorgan disease Treatment Serum IgG4 value (mg/dL) Histology
1 Bösmüller et al. [2] 2011 23 Bilateral Palpable paratesticular multiple indolent floating masses on both sides Paratesticular fibrous pseudotumor Surgical excision of nodules Not described Plasma cell infiltration, IgG4/IgG ratio 44%
2 Bösmüller et al. [2] 2011 25 Right swelling of the right testis with pain Paratesticular inflammatory pseudotumor Semicastration. Not described Dense myofibroblastic proliferation with sparse mitoses, IgG4/IgG ratio 48%
3 Bösmüller et al. [2] 2011 52 Right palpable paratesticular nodules Paratesticular fibrous pseudotumor Surgical excision of nodules Not described Plasma cell infiltration, IgG4/IgG ratio 46%
4 Hart et al. [3] 2012 73 Painless right scrotal mass Paratesticular pseudotumor, Autoimmune pancreatitis, Retroperitoneal fibrosis Right inguinal radical orchiectomy 391 Lymphoplasmacytic infiltration, storiform pattern of fibrosis, IgG4/IgG ratio 60%
5 Migita et al. [4] 2012 74 Left paratesticular mass Paratesticular pseudotumor, Submandibular gland inflammation, prostatitis Left semicastration 505 Fibrosis with lymphocytic and plasmacytic infiltrations, IgG4/IgG ratio 85%
6 Dickmann et al. [5] 2013 19 Right painless intrascrotal mass Spermatic cord inflammatory pseudotumor Local excision Not determined Partially storiform, spindle-like cells and lymphofollicular infiltration, IgG4/IgG ratio 40%
7 Dickmann et al. [5] 2013 28 Right painless intrascrotal mass Spermatic cord inflammatory pseudotumor Local excision Not determined As above
8 de Buy Wenniger et al. [6] 2013 64 Bilateral scrotal pain Testicular pseudotumor, Autoimmune pancreatitis, Retroperitoneal fibrosis Bilateral orchidectomy Not described Plasma cell-rich infiltrate and myofibroblastic spindle cell proliferation around the seminiferous tubules, IgG4/IgG ratio 50% in right testis and 80% in left testis
9 Our case 2014 33 Left palpable scrotal mass Paratesticular pseudotumor, Lung lesion Radical orchidectomy 31.8 Spindle epithelial and polygonal cell proliferation with intense fibrous, plasmacyte, lymphocyte and eosinophil infiltration, IgG4/IgG ratio 50%