Table 1 Correlation between relative miR-106b expression and clinicopathological characteristics in HCCs (n = 104)
From: Upregulation of microRNA-106b is associated with poor prognosis in hepatocellular carcinoma
Characteristics | No. of cases | miR-106b | Pvaluea | |
|---|---|---|---|---|
Low | High | |||
Age (years) | ||||
<50b | 49 | 22 (44.9) | 27 (55.1) | 0.326 |
≥50 | 55 | 30 (54.5) | 25 (45.5) | |
Gender | ||||
Female | 10 | 3 (30.0) | 7 (70.0) | 0.183 |
Male | 94 | 49 (52.1) | 45 (47.9) | |
HBsAg | ||||
Negative | 18 | 12 (66.7) | 6 (33.3) | 0.120 |
Positive | 86 | 40 (46.5) | 46 (53.5) | |
Child-Pugh | ||||
A | 95 | 48 (50.5) | 47 (49.5) | >0.999 |
B | 9 | 4 (44.4) | 5 (55.6) | |
AFP (μg/L) | ||||
<200c | 52 | 30 (57.7) | 22 (42.3) | 0.117 |
≥200 | 52 | 22 (42.3) | 30 (57.7) | |
Tumor size (cm) | ||||
<7d | 50 | 31 (62.0) | 19 (38.0) | 0.019 |
≥7 | 54 | 21 (38.9) | 33 (61.1) | |
Tumor number | ||||
Solitary | 70 | 33 (47.1) | 37 (52.9) | 0.403 |
Multiple | 34 | 19 (55.9) | 15 (44.1) | |
Vascular invasion | ||||
Absent | 82 | 46 (56.1) | 36 (43.9) | 0.016 |
Present | 22 | 6 (27.3) | 16 (72.7) | |
Edmondson-Steiner | ||||
I-II | 60 | 34 (56.7) | 26 (43.3) | 0.112 |
III-IV | 44 | 18 (40.9) | 26 (59.1) | |
TNM stage | ||||
I | 51 | 27 (52.9) | 24 (47.1) | 0.556 |
II-III | 53 | 25 (47.2) | 28 (52.8) | |