Table 2 Univariate and multivariate Cox regression analyses for overall survival
From: Upregulation of microRNA-106b is associated with poor prognosis in hepatocellular carcinoma
Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
miR-106b (high versus low) | 2.445 (1.299-4.605) | 0.004 | 2.002 (1.130-6.977) | 0.027 |
Age (≥50 versus <50 years) | 1.295 (0.691-2.426) | 0.419 | - | - |
Gender (M versus F) | 1.195 (0.368-3.874) | 0.767 | - | - |
HBsAg (positive versus negative) | 1.980 (0.774-5.066) | 0.154 | - | - |
Child-Pugh (B versus A) | 2.027 (0.790-5.199) | 0.141 | - | - |
AFP (≥200 versus <200 μg/L) | 1.926 (1.027-3.612) | 0.041 | 1.263 (0.650-2.453) | 0.491 |
Tumor size (≥7 cm versus <7 cm) | 3.435 (1.746-6.757) | <0.001 | 2.353 (1.133-4.884) | 0.022 |
Tumor number (multiple versus solitary) | 1.745 (0.941-3.235) | 0.077 | - | - |
Vascular invasion (present versus absent) | 2.927 (2.083-7.403) | 0.001 | 2.340 (1.001-5.466) | 0.028 |
Edmondson-Steiner (III-IV versus I-II) | 2.219 (1.006-4.895) | 0.048 | 1.303 (0.534-3.180) | 0.369 |
TNM stage (II-III versus I) | 2.331 (1.391-5.359) | 0.004 | 1.234(0.398-3.822) | 0.716 |