Skip to main content

Table 4 Correlation between elastosis (high/low) and clinico-pathological features

From: Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based study

 

Elastosis (HES slides)

 

Marker

Low elastosis (0–2)

High elastosis (3)

 
 

n (%)*

n (%)*

p-value**

Age

60.0 (5.7)

63.0 (5.2)

NS

Tumour diameter

15,0 (11.3)

14,0 (8.7)

NS

Histological type

  

NS

 Ductal

184 (81)

36 (80)

 

 Lobular

26 (12)

7 (16)

 

 Other

17 (7)

2 (4)

 

Histological grade

  

<0.001

 Grade 1

53 (23)

22 (49)

 

 Grade 2

117 (52)

22 (49)

 

 Grade 3

57 (25)

1 (2)

 

Nodal status

  

NS

 N0

147 (65)

34 (76)

 

 N1+

80 (35)

11 (24)

 

ER

  

0.005

 Positive

192 (85)

45 (100)

 

 Negative

35 (15)

0 (0)

 

PR

  

0.04

 Positive

145 (64)

36 (80)

 

 Negative

82 (36)

9 (20)

 

HER2

  

0.03

 Negative

204 (90)

45 (100)

 

 Positive

23 (10)

0 (0)

 

Ki67

12,0 (15,2)

7,0 (6,6)

<0.001

Tumour shape

  

<0.001

 Star

136 (60)

44 (98)

 

 Round

89 (40)

1 (2)

 

Fibrotic focus

  

0.011

 No

197 (87)

45 (100)

 

 Yes

29 (13)

0 (0)

 

Necrosis

  

0.015

 No

200 (88)

45 (100)

 

 Yes

27 (12)

0 (0)

 
  1. *Number of cases (n and %) is given except for age, tumour diameter and Ki67, where median and standard deviation (SD) is given.
  2. **Pearson's chi-square test except for age, tumour diameter and Ki67 where Mann–Whitney U test was applied.