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Table 4 Correlation between elastosis (high/low) and clinico-pathological features

From: Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based study

  Elastosis (HES slides)  
Marker Low elastosis (0–2) High elastosis (3)  
  n (%)* n (%)* p-value**
Age 60.0 (5.7) 63.0 (5.2) NS
Tumour diameter 15,0 (11.3) 14,0 (8.7) NS
Histological type    NS
 Ductal 184 (81) 36 (80)  
 Lobular 26 (12) 7 (16)  
 Other 17 (7) 2 (4)  
Histological grade    <0.001
 Grade 1 53 (23) 22 (49)  
 Grade 2 117 (52) 22 (49)  
 Grade 3 57 (25) 1 (2)  
Nodal status    NS
 N0 147 (65) 34 (76)  
 N1+ 80 (35) 11 (24)  
ER    0.005
 Positive 192 (85) 45 (100)  
 Negative 35 (15) 0 (0)  
PR    0.04
 Positive 145 (64) 36 (80)  
 Negative 82 (36) 9 (20)  
HER2    0.03
 Negative 204 (90) 45 (100)  
 Positive 23 (10) 0 (0)  
Ki67 12,0 (15,2) 7,0 (6,6) <0.001
Tumour shape    <0.001
 Star 136 (60) 44 (98)  
 Round 89 (40) 1 (2)  
Fibrotic focus    0.011
 No 197 (87) 45 (100)  
 Yes 29 (13) 0 (0)  
Necrosis    0.015
 No 200 (88) 45 (100)  
 Yes 27 (12) 0 (0)  
  1. *Number of cases (n and %) is given except for age, tumour diameter and Ki67, where median and standard deviation (SD) is given.
  2. **Pearson's chi-square test except for age, tumour diameter and Ki67 where Mann–Whitney U test was applied.