Figure 2
From: Clinico-pathologic spectrum of C3 glomerulopathy-an Indian experience
Photomicrographs showing immunofluorescence pattern and EM of DDD and C3GN. (a) DDD-IF with C3, coarse staining of glomerular capillary loops and Bowmans capsule. (arrows) (b) Predominant mesangial rings with focal glomerular capillaries. (c) DDD - EM is showing glomerular capillary intramembranous dense osmiophilic material of variable thickness. (d) Osmiophilic material in the mesangium (star), subendothelial (red arrow), subepithelial humps (broad white arrows) (Uranyl acetate, b-2800, c-X36,00). (e) C3GN - IF Intense granular positivity in the mesangium and glomerular membranes. (f) EM - Subendothelial (red arrow) and mesangial (black arrow) (Uranyl acetate,X10,000).