Figure 1From: Valsartan blocks thrombospondin/transforming growth factor/Smads to inhibit aortic remodeling in diabetic rats Biochemical characteristics of thoracic aortas. Measurements of fasting plasma glucose (A) and fasting insulin (B) before STZ injection (4 week), 1 week after STZ injection (6 week) and the end of the experiment (22 week), with ISI (C) calculated. *P < 0.05 and **P < 0.01, vs controls. Abbreviations: ISI, insulin sensitivity index; STZ, streptozotocin.Back to article page