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Table 3 Response to treatment according to TTF1-expression (n = 178)

From: Value of thyroid transcription factor (TTF)-1 for diagnosis and prognosis of patients with locally advanced or metastatic small cell lung cancer

 

TTF1 + 150 (84.3%)

TTF1 –n = 28 (15.7%)

p-value

CR

8 (5.3%)

4 (14.3%)

 

PR

105 (70.0%)

16 (57.1%)

 

SD

22 (14.7%)

0

 

PD

15 (10.0%)

8 (28.6%)

0.003

RR

75.3%

71.4%

0.642

DCR (overall)

135 (90.0%)

20 (71.4%)

0.013

DCR stage III

56/58 (96.6%)

10/10 (100%)

0.726

DCR stage IV

79/92 (85.9%)

10/18 (55.6%)

0.006

  1. Overall response rate (RR) is defined as the proportion of patients having at least a partial response according to RECIST1.0. Disease control rate (DCR) is defined as all patients with at least a stable disease according to RECIST1.0. (CR = complete response; PR = partial response; SD = stable disease; PD = progressive disease).
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Diagnostic Pathology

ISSN: 1746-1596

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