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Table 2 Univariate and multivariate analyses of prognostic factors in patients with pancreatic cancer

From: Expression and clinical significance of HSPA2 in pancreatic ductal adenocarcinoma

Variables

Univariable P -value (log-rank test)

Multivariable

HR (95% CI)

P -value

Age at diagnosis (years)

   

<60 vs. ≥60

0.584

  

Gender

   

Male vs. Female

0.763

  

Tumor size (cm)

   

<2 vs. ≥2

0.082

  

Histological grades

   

Well/Moderate vs. Poor

0.067

  

TNM stagea

   

IA-IB vs. IIA-IIB

0.013

1.23 (1.14-1.52)

0.026

Lymph node metastasis

   

No vs. Yes

0.040

1.14 (0.97-1.41)

0.054

Vascular invasion

   

No vs. Yes

0.017

1.27 (1.04-1.49)

0.042

CA19-9 (U/ml)

   

<27 vs. ≥27

0.082

  

Bilirubin (μmol/l)

   

<17.1 vs. ≥17.1

0.185

  

HSPA2 mRNA expression

   

Low vs. High

0.007

1.58 (1.11-1.89)

0.011

  1. aTNM staging was classified according to the 7th edition of the AJCC cancer staging manual.
  2. HSPA2, Heat shock-related 70 kDa protein 2.