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Figure 3 | Diagnostic Pathology

Figure 3

From: miR-203 inhibition of renal cancer cell proliferation, migration and invasion by targeting of FGF2

Figure 3

miR-203 directly targets FGF2 in renal cancer cells. A. The wild type and mutant complementary sequences of the FGF2 mRNA 3’UTR are shown with the miR-203 sequence. B. Luciferase assay in 786-O cells co-transfected with miR-203 mimic and a luciferase reporter containing the FGF2 3’UTR (Wt) or a mutant (Mut). C. Overexpression of miR-203 inhibited the expression of FGF2 at the protein level in 786-O cells. D. Down-regulated expression of miR-203 increased the expression of FGF2 at the protein level in 786-O cells. * P <0.05.

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