Table 3 Univariate and multivariate Cox hazard regression analysis for prognostic factors
Univariate analysis | Multivariate analysis | ||
|---|---|---|---|
Hazard ratio (95% confidence interval) | P value | Hazard ratio (95% confidence interval) | |
Gender | |||
Male vs female | 1.349(0.458-3.973) | 0.587 | |
Age | |||
≥60 vs <60 | 1.849(0.760-4.498) | 0.176 | |
Smoking | |||
Smoker vs Nonsmoker | 0.848(0.250-2.868) | 0.790 | |
Drinking | |||
Drinker vs nondrinker | 0.818(0.345-1.942) | 0.649 | |
Differentiation | |||
Poor vs moderate vs well | 0.762(0.415-1.399) | 0.381 | |
Tumor depth (PT) | |||
T4vs T3 vs T2 vs T1 | 2.173(1.380-3.422) | 0.001* | |
Lymph node metastasis | |||
Positive vs negative | 4.243(1.844-9.764) | 0.001* | |
Clinical stage | |||
IVvs IIIvs IIvsI | 5.513(2.300-13.214) | P < 0.001* | 6.998(2.217-22.083) |
miR-23a expression | |||
High vs low | 7.419(2.561-21.491) | P < 0.001* | 6.712(2.076-21.700) |