Table 2 Comparison of flow cytometric features among normal, non-clonal cytopenias and MDS

Granulocytic series

SSC

521 (396–658)

534 (340–628)

394 (236–619)

462 (319–648)

<0.0001

CD45 MFI

138-577

265 (107–683)

216 (34–770)

270 (89–551)

0.02

Asynchronous shift to the left

7 (21%)

11 (26%)

6 (46%)

0.12

Monocytic series

SSC

253 (196–399)

237 (149–390)

233 (66–399)

203 (184–322)

0.01

% monocytes

0.8-3.6

3.0 (0.7 - 8.8)

3.7 (0.2 - 18)

3.3 (0.1 - 21)

0.22

% CD16⁺ monocytes

<0.48

0.3 (0.1 - 3.4)

0.4 (0.02 - 10)

0.9 (0.05 - 4)

0.003

Cells in the blast gate

BM % blasts (cytology)

1.0 (0.5 - 4.0)

1.0 (0.5 - 5)

12 (7.7 - 18)

% CD34⁺ cells

<1.59

0.6 (0.02-2.1)

1.0 (0.02- 5.1)

3.6 (0.2 - 28)

<0.0001

% B cell precursors/total cells

>0.05 (0.04-0.53)

0.06 (0–0.7)

0.06 (0–0.7)

0.01 (0.01 - 0.14)

<0.0001

%CD34⁺/CD13⁺/CD117⁺

<0.62

0.3 (0.01-0.8)

0.5 (0.01-4.2)

1.4 (0–24.1)

0.001

% CD34⁺/CD7⁺

<0.08

0.05 (0–0.09)

0.04 (0–0.7)

0.13 (0.04-26)

<0.0001

% CD34⁺/CD56⁺

<0.05

0.01 (0–0.09)

0.03 (0–1.9)

0.13 (0.02-27)

<0.0001

Total abnormalities

0 (0–2)

2 (0–5)

7 (3–13)

9 (6–16)

<0.0001