Table 2 Genotype and allele distributions in patients with CAD and control participants
rs4577202(SNP1) | rs7250152(SNP2) | rs10853784(SNP3) | Â | Â | Â | Â | Â | Â | Â | Â | Â |
|---|---|---|---|---|---|---|---|---|---|---|---|
Variant | CAD n(freq) | Control n(freq) | P value | Variant | CAD n(freq) | Control n(freq) | P value | Variant | CAD n(freq) | Control n(freq) | P value |
Genotype | Â | Â | Â | Genotype | Â | Â | Â | Genotype | Â | Â | Â |
AA | 325(0.644) | 309(0.658) | 0.814 | TT | 166(0.328) | 132(0.282) | 0.277 | TT | 20(0.040) | 27(0.058) | 0.016 |
AG | 156(0.309) | 141(0.301) | Â | CT | 237(0.470) | 234(0.499) | Â | CT | 151(0.299) | 173(0.369) | Â |
GG | 24(0.047) | 19(0.041) | Â | CC | 102(0.202) | 103(0.219) | Â | CC | 334(0.661) | 269(0.574) | Â |
Dominant model | Â | Â | Â | Dominant model | Â | Â | Â | Dominant model | Â | Â | Â |
AA | 325(0.644) | 309(0.658) | 0.617 | TT | 166(0.328) | 132(0.282) | 0.110 | CC | 334(0.661) | 269(0.574) | 0.004 |
AG + GG | 180(0.356) | 160(0.342) | Â | CT + CC | 339(0.672) | 337(0.719) | Â | CT + TT | 170(0.339) | 200(0.426) | Â |
Recessive model | Â | Â | Â | Recessive model | Â | Â | Â | Recessive model | Â | Â | Â |
GG | 24(0.047) | 19(0.041) | 0.575 | CC | 102(0.202) | 103(0.219) | 0.500 | TT | 20(0.040) | 27(0.058) | 0.191 |
AA + AG | 481(0.953) | 454(0.959) | Â | CT + TT | 403(0.798) | 366(0.781) | Â | CT + CC | 485(0.960) | 442(0.942) | Â |
Additive model | Â | Â | Â | Additive model | Â | Â | Â | Additive model | Â | Â | 0.021 |
AG | 156(0.309) | 141(0.301) | 0.779 | CT | 237(0.470) | 234(0.499) | 0.335 | CT | 151(0.299) | 173(0.369) | Â |
AA + GG | 349(0.691) | 328(0.699) | Â | CC + TT | 268(0.530) | 235(0.501) | Â | CC + TT | 354(0.701) | 296(0.631) | Â |
Allele | Â | Â | Â | Allele | Â | Â | Â | Allele | Â | Â | Â |
A | 806(0.799) | 759(0.809) | 0.536 | T | 569(0.563) | 498(0.532) | 0.150 | T | 191(0.193) | 227(0.241) | 0.004 |
G | 204(0.201) | 179(0.191) | Â | C | 441(0.437) | 440(0.468) | Â | C | 819(0.807) | 711(0.759) | Â |