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Table 2 Enriched KEGG pathways in different contrastive groups

From: Gene expression of OCT4, SOX2, KLF4 and MYC (OSKM) induced pluripotent stem cells: identification for potential mechanisms

   KEGG pathway Count P value
HFF1_24 h vs HFF1 Up-regulated gene hsa04622: RIG-I-like receptor signaling pathway 6 9.35E-05
hsa04620: Toll-like receptor signaling pathway 5 0.0043
hsa04623: Cytosolic DNA-sensing pathway 4 0.0057
HFF1_48 h vs HFF1 Up-regulated gene hsa04620: Toll-like receptor signaling pathway 6 0.0209
hsa04622: RIG-I-like receptor signaling pathway 5 0.0249
Down-regulated gene hsa05410: Hypertrophic cardiomyopathy (HCM) 4 0.0479
HFF1_72 h vs HFF1 Up-regulated gene hsa00330: Arginine and proline metabolism 6 0.0076
hsa00480: Glutathione metabolism 5 0.0287
hsa00250: Alanine, aspartate and glutamate metabolism 4 0.0349
Down-regulated gene hsa04510: Focal adhesion 13 4.57E-05
hsa04810: Regulation of actin cytoskeleton 10 0.0056
hsa05200: Pathways in cancer 11 0.0272
ES vs HFF1 Up-regulated gene hsa05217: Basal cell carcinoma 14 9.58E-06
hsa04310: Wnt signaling pathway 22 1.28E-04
hsa05200: Pathways in cancer 36 2.29E-04
hsa00330: Arginine and proline metabolism 10 0.0029
Down-regulated gene hsa04510: Focal adhesion 40 8.73E-08
hsa00520: Amino sugar and nucleotide sugar metabolism 13 1.09E-04
hsa04512: ECM-receptor interaction 18 2.52E-04
hsa04142: Lysosome 20 0.0019
iPS vs HFF1 Up-regulated gene hsa04310: Wnt signaling pathway 16 2.39E-04
hsa05217: Basal cell carcinoma 8 0.0029
hsa00250: Alanine, aspartate and glutamate metabolism 6 0.0041
hsa00260: Glycine, serine and threonine metabolism 6 0.0041
Down-regulated gene hsa04510: Focal adhesion 56 1.46E-11
hsa04512: ECM-receptor interaction 27 3.06E-07
hsa00520: Amino sugar and nucleotide sugar metabolism 16 2.84E-05
hsa04810: Regulation of actin cytoskeleton 42 1.43E-04