Resection specimens. A) Gross section image showing the opened sigmoid colon with a deep ulcer. B) Low power image of the gut wall showing the transition from unaffected mucosa to ulcer (notice the nodules and the marked fibrosis in the deep parts of the gut wall). C) High power image of a nodule showing Hodgkin and Reed-Sternberg cells in an inflammatory environment. D) High power image showing Hodgkin and Reed-Sternberg cells positive for CD15. E) High power image showing Hodgkin and Reed-Sternberg cells positive for CD30. F) High power image demonstrating Epstein-Barr virus by positive fluorescence in situ hybridization reaction for Epstein-Barr virus encoded small RNA’s (EBER).