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Figure 2 | Diagnostic Pathology

Figure 2

From: MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma

Figure 2

Kaplan-Meier analysis of DFS and OS based on the expression of miRNAs. A) PDAC patients with high level of miR-198 have shorter DFS compared to patients with low level of this miRNA (P = 0.0001). B) PDAC patients with high level of miR-21 have shorter DFS compared to patients with low level of this miRNA (P = 0.0011). C) Combined analysis of miR-21 and miR-198 – PDAC patients with low levels of both miR-21 and miR-198 have longer DFS compared to patients with high levels of miR-21 and/or miR-198 (P < 0.0001). D) PDAC patients with high level of miR-198 have shorter OS compared to patients with low level of this miRNA (P = 0.0097). E) PDAC patients with high level of miR-21 have shorter OS compared to patients with low level of this miRNA (P = 0.0427). F) Combined analysis of miR-21 and miR-198 – PDAC patients with low levels of both miR-21 and miR-198 have longer OS compared to patients with high levels of miR-21 and/or miR-198 (P = 0.0015).

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Diagnostic Pathology

ISSN: 1746-1596

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