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Table 2 Pfcrt haplotypes and frequency of Pfmdr1 codons in Nigerian children

From: Persistence of chloroquine-resistant haplotypes of Plasmodium falciparum in children with uncomplicated Malaria in Lagos, Nigeria, four years after change of chloroquine as first-line antimalarial medicine

Gene

n

Genotype/haplotype

Prevalence (%)

Pfcrt

119

CVIET (mutant type)

109 (91.6)

Amino acids (72–76)

 

CVMNK (wild type)

5 (4.2)

 

CVMNK/CVIET (mixed)

5 (4.2)

Pfmdr1

   

Amino acids 86, 184, 1034, 1042 and 1246

74

86Y (mutant type)

46 (62.2)

  

86 N (wild type)

14 (18.9)

  

86 N + 86Y (mixed)

14 (18.9)

 

71

184 F (mutant type)

49 (69)

  

184Y (wild type)

11 (15.5)

  

184 F + 184Y (mixed)

11 (15.5)

 

81

1034C (mutant type)

0(0)

  

1034S (wild type)

81(100)

 

81

1042D (mutant type)

0(0)

  

1042 N (wild type)

81(100)

 

29

1246S (mutant type)

0(0)

  

1246D (wild type)

29(100)