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Table 1 A comparison of the clinical and histological features of KD with ALHE

From: Kimura disease accompanied with Nephrotic syndrome in a 45-year-old male

  Kimura disease Angiolymphoid hyperplasia with eosinophilia
clinical features   
Sex Female predominance (70%) Male predominance (85%)
Age Young adulthood Young to middle age
Race More common in Asians Occurs in all races
Location Head and neck Head and neck
Presentation Localized subcutaneous mass Dermal papules or nodules
Number Single or multiple Usually multiple
Size Average 3 cm Average 1 cm
Lymph node involvement Common Rare
peripheral eosinophilia Almost invariably present Rare (20%)
Serum immunoglobulin E (IgE) level Elevated Normal
Renal involvement Occasional (21%) Rare
Recurrence rate 30% 15-40%
Histopathological features   
Depth Subcutaneous, muscle Cutaneous, subcutaneous
Vascular proliferation Some degree of vascular proliferation Florid vascular proliferation
Lymphoid follicles Always found May be present
Eosinophils Abundant Sparse to abundant
Eosinophils abscesses Present Not seen
Endothelium Flattened Cuboidal to dome shaped:"Histiocytoid"
Fibrosis Present Absent