Diagnostic and prognostic potential of miR-21, miR-29c, miR-148 and miR-203 in adenocarcinoma and squamous cell carcinoma of esophagus

Diagnostic Pathology

Table 2 MiRNA expression levels in adenocarcinoma and paired non-tumoral esophageal mucosa

	Adenocarcinoma (n = 17)	Mucosa (n = 17)	FC	p-value
	Median	Median
	(25%–75% percentile)	(25%–75% percentile)
miR-203	2,312	12,28	0,19	< 0,0001
	(0,5304–5,990)	(9,139–19,73)
miR-21	2,463	0,06064	40,38	0,0004
	(0,8149–9,648)	(0,06729–0,9838)
miR-25	0,07557	0,07959	0,95	0,6221
	(0,02829–0,3545)	(0,02275–0,2205)
miR-27a	1,763	2,74	0,64	0,1006
	(1,236–3,482)	(2,096–5,082)
miR-31	0,6739	0,4659	1,45	0,1201
	(0,3100–2,596)	(0,4084–0,8982)
miR-200c	1,718	1,884	0,92	0,2036
	(1,182–2,705)	(1,496–4,017)
let-7a	0,15	0,196	0,77	0,3394
	(0,1143–0,4092)	(0,04641–0,2439)
miR-29c	0,03389	0,1647	0,21	0,9697
	(0,01787–0,7736)	(0,0233–0,6866)
miR-148	0,1779	0,1785	1,00	0,1893
	(0,1244–0,3107)	(0,1050–0,5636)