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Table 3 Diagnostic accuracy of each analysed markers

From: Assessment of a panel of tumor markers for the differential diagnosis of benign and malignant effusions by well-based reverse phase protein array

Tumor markers

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Accuracy (%)

Cytology

57.3

92.3

93.5

52.9

69.3

MUC1

52.0

92.3

92.9

50.0

65.8

EMA

48.0

92.3

92.3

48.0

63.2

Pan-CK

36.0

92.3

90.0

42.9

55.3

HSP90

14.7

92.3

78.6

36.0

41.2

TGF-β

4.0

92.3

50.0

33.3

34.2

MUC 1 + EMA

57.3

92.3

93.5

52.9

69.3

MUC 1 + EMA+ Pan-CK

64.0

89.7

92.3

56.5

72.8

MUC 1 + EMA+ Pan-CK + HSP90

70.7

82.1

88.3

59.3

74.6

MUC 1 + EMA+ Pan-CK + HSP90 + TGF-β

72.0

82.1

88.5

60.4

75.4

  1. PPV, positive predictive value; NPV, negative predictive value