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Table 2 Characteristics of the studies according to molecular subtypes

From: Prognostic significance of c-Met in breast cancer: a meta-analysis of 6010 cases

First author

Year

Patients Number

Patient source

Technique

Type of patients

HR estimation

HR(95%CI) of OS

HR(95%CI) of RFS

Vendrell

2008

33

France

PCR

ER positive BC

Given by author

1.08 (0.40-2.88)

1.38 (0.60-3.21)

Ponzo

2009

60

Canada

IHC

Basal-like BC

Given by author

NA

3.02 (0.31-29.30)

  

447

Canada

IHC

Nonbasal-like BC

Given by author

NA

1.49 (0.86-2.62)

Raghav

2012

64

USA

RPPA

TNBC

Given by author

NA

2.36 (0.86-6.51)

  

140

USA

RPPA

hormone receptor positive BC

Given by author

8.28 (1.10-62.59)

3.44 (1.21-9.81)

Gonzalez-Angulo

2013

173

USA

MIP

TNBC

Given by author

NA

1.33 (0.51-3.43)

  

583

USA

MIP

hormone receptor positive BC

Given by author

NA

1.86 (1.07-3.25)

  

207

USA

MIP

HER-2 positive BC

Given by author

NA

0.92 (0.29-2.95)

Zagouri

2013

170

Austria

IHC

TNBC

Given by author

3.74(1.65-8.46)

3.43 (1.65-7.12)

Zagouri

2014

78

Austria

IHC

ER and HER-2 positive BC

Given by author

1.32 (0.91-1.90)

1.22 (0.91-1.63)

Inanc

2014

97

Turkey

IHC

TNBC

Given by author

1.15 (0.54-2.44)

2.05 (0.96-4.36)

  1. Note: IHC, immunohistochemistry; RPRP, Reverse phase protein lysate microarray; FISH, Fluorescence in situ hybridization; MIP, Molecular Inversion Probes; BC, breast cancer; TNBC, triple negative breast cancer; OS, over survival; RFS, Relapse-free survival; NA, not available.cpc