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Table 1 Clinical characteristics and proportions of lymphocyte subsets in peripheral blood of Chinese patients with SLE and healthy controls

From: Increased Tim-3 expression on peripheral T lymphocyte subsets and association with higher disease activity in systemic lupus erythematosus

  SLE Controls
N 46 28
Age, yr 34.6 ± 12.7 34.8 ± 13.6
Female, n (%) 42 (91.3) 25 (89.3)
Male, n (%) 4 (8.7) 3 (10.7)
ANA (+), n (%) 46 (100) 0
C3, g/L 0.76 ± 0.36 -
C4, g/L 0.16 ± 0.12 -
SLEDAI score 8.6 ± 4.3 -
WBCs (×109/L) 5.15 ± 2.91 5.88 ± 1.34
Lymphocytes, %a 15.54 ± 10.93* 21.26 ± 5.86
CD3+CD4+ T subset, %b 21.96 ± 9.11* 30.58 ± 7.75
CD3+CD4- T subset, %b 26.28 ± 11.81 24.27 ± 7.99
Ratio of CD3+CD4+/CD3+CD4- T 0.97 ± 0.50* 1.38 ± 0.54
  1. Values shown are mean ± SD, unless otherwise noted
  2. ANA, anti-nuclear antibody; C, complement; SLEDAI, systemic lupus erythematosus disease activity index; WBCs, white blood cells
  3. aPercentage of total white blood cells in peripheral blood
  4. bPercentage of total lymphocytes in peripheral blood
  5. *p < 0.05 compared to healthy control group