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Table 1 Clinical characteristics and proportions of lymphocyte subsets in peripheral blood of Chinese patients with SLE and healthy controls

From: Increased Tim-3 expression on peripheral T lymphocyte subsets and association with higher disease activity in systemic lupus erythematosus

 

SLE

Controls

N

46

28

Age, yr

34.6 ± 12.7

34.8 ± 13.6

Female, n (%)

42 (91.3)

25 (89.3)

Male, n (%)

4 (8.7)

3 (10.7)

ANA (+), n (%)

46 (100)

0

C3, g/L

0.76 ± 0.36

-

C4, g/L

0.16 ± 0.12

-

SLEDAI score

8.6 ± 4.3

-

WBCs (×109/L)

5.15 ± 2.91

5.88 ± 1.34

Lymphocytes, %a

15.54 ± 10.93*

21.26 ± 5.86

CD3+CD4+ T subset, %b

21.96 ± 9.11*

30.58 ± 7.75

CD3+CD4- T subset, %b

26.28 ± 11.81

24.27 ± 7.99

Ratio of CD3+CD4+/CD3+CD4- T

0.97 ± 0.50*

1.38 ± 0.54

  1. Values shown are mean ± SD, unless otherwise noted
  2. ANA, anti-nuclear antibody; C, complement; SLEDAI, systemic lupus erythematosus disease activity index; WBCs, white blood cells
  3. aPercentage of total white blood cells in peripheral blood
  4. bPercentage of total lymphocytes in peripheral blood
  5. *p < 0.05 compared to healthy control group