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Table 1 The relationship between the LOH frequency at D8S262 and clinical features of patients with hepatocellular carcinoma

From: Loss of heterozygosity at D8S262: an early genetic event of hepatocarcinogenesis

Wk13374861variables Informative cases (n) LOH (%) χ 2 P
Age (years)     
  ≤ 52 (n = 68) 49 72.06 2.664 0.103
  > 52 (n = 60) 44 73.33   
Sex     
 Male (n = 108) 79 73.15 0.084 0.772
 Female (n = 20) 14 70   
AFP     
  ≥ 20 ng/mL (n = 76) 58 76.32 1.261 0.261
  < 20 ng/mL (n = 52) 35 67.31   
HBsAg or HCV     
  + (n = 86) 62 72.09 0.042 0.838
 - (n = 42) 31 73.81   
HCC differentiation     
 Grade I (n = 14) 9 64.29 0.600 0.741
 Grade II (n = 78) 57 73.08   
 Grade III (n = 36) 27 75   
Tumor size     
  ≥ 5 cm (n = 68) 49 72.06 0.026 0.872
  < 5 cm (n = 60) 44 73.33   
Extrahepatic metastasis     
 Presence (n = 42) 31 73.81 0.978 0.323
 Absence (n = 86) 62 72.09