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Table 1 The relationship between the LOH frequency at D8S262 and clinical features of patients with hepatocellular carcinoma

From: Loss of heterozygosity at D8S262: an early genetic event of hepatocarcinogenesis

Wk13374861variables

Informative cases (n)

LOH (%)

χ 2

P

Age (years)

    

  ≤ 52 (n = 68)

49

72.06

2.664

0.103

  > 52 (n = 60)

44

73.33

  

Sex

    

 Male (n = 108)

79

73.15

0.084

0.772

 Female (n = 20)

14

70

  

AFP

    

  ≥ 20 ng/mL (n = 76)

58

76.32

1.261

0.261

  < 20 ng/mL (n = 52)

35

67.31

  

HBsAg or HCV

    

  + (n = 86)

62

72.09

0.042

0.838

 - (n = 42)

31

73.81

  

HCC differentiation

    

 Grade I (n = 14)

9

64.29

0.600

0.741

 Grade II (n = 78)

57

73.08

  

 Grade III (n = 36)

27

75

  

Tumor size

    

  ≥ 5 cm (n = 68)

49

72.06

0.026

0.872

  < 5 cm (n = 60)

44

73.33

  

Extrahepatic metastasis

    

 Presence (n = 42)

31

73.81

0.978

0.323

 Absence (n = 86)

62

72.09

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