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Table 3 Clinical, radiographic, laboratory and pathological features of twelve high-probability IgG4-TIN cases

From: Evaluation of diagnostic criteria for IgG4-related tubulointerstitial nephritis

Pt No. Age/Gender Clinical Diagnosis Proteinuria (0.01-0.15g/24h) Hematuria ALB (35-55 g/L) SCr (44-132μmol/L) eGFR (80-120ml/min) Serum IgG (751-1560mg/dL) Serum C3 (79-152 mg/dL) Principal Pathological Diagnosis IgG4 (cells/HPF) IgG4/IgG (%) Storiform fibrosis Stage of Fibrosis TBM Deposits Imaging Findings Other Organ Involvement
1 65 M ARF 0.30 - 36 381 13.2 1910 67 Idiopathic TIN 14 23.3 - 0 - Bilateral Enlarged -
2 42 F ARF, AAV 1.41 4+ 35 447 9.9 2370 78 Pauci-immune CreGN 22 56.7 - 0 + - -
3 52 F SLE, CRF 1.57 2+ 30 273 15.5 3050 86 LN 11 84.6 - 1 + - PF
4 76 M CGN, CRF 1.41 4+ 33 380 11.9 1990 75 Immune complex CreGN 10 43.5 - 1 - - PF
5 62 M CGN, CRF 1.17 - 30 234 25.6 4050 45 Idiopathic TIN 55 93.2 + 2 + Bilateral Enlarged PF Lymph node Enlarged
6 49 M CGN, CRF 0.40 3+ 37.6 138 52 1050 81 IgAN 12 32.2 - 1 + - PF
7 33 F ARF 0.21 - 39.9 231 24.9 2010 123 Drug-induced TIN 22 58 - 1 + - -
8 59 M ARF 0.60 3+ 26.6 1108 10.7 1380 86 Anti-GBM CreGN 29 60.3 - 1 - - PF
9 36 F CGN, CRF 2.69 3+ 30.4 199 40.7 1910 121 IgAN 14 40.3 - 2 + - -
10 56 F ARF, AAV 1.58 3+ 26.9 1832 5.4 2120 80 Crescentic IgAN 20 95 + 1 + - PF
11 59 M ARF 0.49 - 25.7 586 8.4 1860 106 Immune complex CreGN 52 91 + 2 + Bilateral Enlarged -
12 30 F CGN,CKD2 0.61 - 42.1 105 65.3 1870 109 IgAN 25 63.7 - 2 + - -
  1. CreGN, Crescentic Glomerulonephritis; AAV, antineutrophil cytoplasmic autoantibody-associated vasculitis; PF, pulmonary fibrosis; LN, lupus nephritis; IgAN, IgA nephropathy; GBM, glomerular basement membrane.