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Table 2 Characteristics of 47 hepatocellular carcinoma patients with initial extrahepatic metastases

From: Extrahepatic metastases as initial manifestations of hepatocellular carcinoma: an Egyptian experience

  Number Percent
Male/Female 38/9
Age range 40–80 years
Median age 60 years
HCV 47 100
HBV 1 2.1
Elevated AFP 22 46.8
Cirrhosis 36 76.6
Hepatic focal lesion:   
-Solitary 38 80.9
-Multiple 9 19.1
Site of metastases:   
- Bones 17 36.2
-Lymph nodes 9 19.1
- Soft tissue 7 15
- Omentum 7 15
-Maxillary sinus 2 4.2
-Adrenal gland 2 4.2
-Brain 2 4.2
-Skin 1 2.1
Pattern of HCC growth :   
-Trabecular (plate like) 8 17 %
- Pseudoglandular (acinar) 2 4.3 %
-Solid 10 21.3 %
-Mixed patterns 27 57.4 %
Grade:   
- Well differentiated 0 0 %
- Moderately differentiated 17 36.2 %
- Poorly differentiated 30 63.8 %
  1. HCV hepatitis C virus, HBV hepatitis B virus, AFP α fetoprotein