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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Combination of serum RASSF1A methylation and AFP is a promising non-invasive biomarker for HCC patient with chronic HBV infection

Fig. 2

Receiver operating characteristic (ROC) curve analyses using serum RASSF1A methylation and AFP for the discrimination of patients with HCC from patients with CHB. Positive serum RASSF1A methylation yielded an AUC of 0.796 (95 % CI: 0.721–0.864) with a sensitivity of 64.2 % and a specificity of 89.8 % for the discrimination of patients with HCC from patients with CHB; serum AFP at the cut-off value (≥20 ng/mL) yielded an AUC of 0.756 (95 % CI: 0.652–0.805) with a sensitivity of 62.1 % and a specificity of 80.7 %; combined, both indicators yielded an AUC of 0.876 (95 % CI: 0.781–0.933) with a sensitivity of 80.9 % and a specificity of 93.4 %

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