Table 1 Clinicopathological features of intracranial malignant solitary fibrous tumors

Ng et al. 2000 [4]

55/F

posterior fossa/cerebellum

cellular pleomorphism, no mitoses in PT; 3–4 mitoses/10HPFs in RT, the same Ki-67 LI of 3 %

3 recurrences over 10years, metastasis to the soft tissues and lungs

Barron et al. 2001 [5]

61/F

frontal

hypercellularity, marked pleomorphism, 4 mitoses/10 HPFs

10 months (postoperative radiation herapy given)

Martin et al. 2001 [6]

71/F

dura around the sagittal sinus

marked pleomorphism, 6 mitoses /10 HPFs

death 1 month after the diagnosis

Kim et al. 2004 [7]

55/M

posterior fossa

hypercellularity and more than 4 mitoses/10HPFs, pleomorphism, hemorrhage, and necrosis

9 years,disseminated to the spine, lung, and liver

Miyashita et al. 2004 [8]

63/F

falcotentorial

the MIB-1 LI increased from less than 1 % in the PT to 13 % in the latest tumor

several recurrences over 15 years, dissemination to the cerebrospinal fluid

Ogawa et al. 2004 [9]

70/F

meninge

Ki67 LI and mitosis rates were 3.1 ± 1.2 % and less than 1/10HPF in the PT and 16.1 ± 6.4 % and 6/10HPF in the last (5th) one

4 recurrences over 26 years, metastasis to the right lung and focal invasion into the cerebellum

Pizem et al. 2004 [10]

60/F

dura-based, left frontal

the mitoses increased from less than 1/10HPF in the PT to 16/10HPF in the latest tumor

4 recurrences over a 30-year period

Lawlor et al. 2008 [11]

77/M

dural-based, left parietal

invasion into the sagittal sinus, 19 mitoses/10HPFs, marked amianthoid fibre deposition

not known

Hu et al. 2009 [12]

54/M

dural-based, left occipital

hypercellularity, rare mitoses in PT, >20 mitoses/10 HPFs in RT

died 16 month later due to recurrence and metastasis to bilateral lungs

Zhang et al. 2010 [13]

49/F

pineal region

hypercellularity, 5 mitoses/10HPFs, and MIB-1 LI (7.3 ± 1.8 %)

10 months (postoperative radiotherapy not performed)

Choi et al. 2011 [14]

39/F

left occipital lobe

hypercellularity, pleomorphism, Ki-67 LI increased from 10 % (average, 1 %) in PT to 25 % in RT with infiltrative brain invasion and 15 mitoses/10HPFs

recurrences over a 6-months period