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Fig. 1 | Diagnostic Pathology

Fig. 1

From: RETRACTED ARTICLE: The microRNA-325 inhibits hepatocellular carcinoma progression by targeting high mobility group box 1

Fig. 1

miR-325 is decreased and inversely relates to HMGB1 expression in HCC patients. a Box-plot analysis of miR-325 and HMGB1 levels in 99 HCC patient samples and corresponding adjacent tissues. T refers to tumor tissues and P refers to corresponding adjacent tissues. b A negative correlation was found between RNA expression of miR-325 and HMGB1 in tumor samples (P < 0.0001). c Kaplan–Meier overall and progression-free survival curves for liver cancer patients with high and low miR-325 expression. Liver cancer patients with low miR-325 expression had significantly shorter overall (P < 0.05) and progression-free (P < 0.05) survival than those with high miR-325 expression did. Data were shown as mean ± SEM of three independent experiments. * indicates P < 0.05

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