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Table 1 The clinical characteristics relevance analysis of miR-325 and HMGB1 in patients with HCC

From: RETRACTED ARTICLE: The microRNA-325 inhibits hepatocellular carcinoma progression by targeting high mobility group box 1

Characteristics

All Patients

miR-325 low Expression (≤ Mediana)

miR-325 high Expression (> Mediana)

p value

HMGB1 low Expression (< Medianb)

HMGB1 high Expression (≥ Medianb)

p value

NO.

99

51

48

 

49

50

 

Age(years)

   

0.832

  

0.565

<60

43

21

22

 

23

20

 

≥60

56

28

28

 

26

30

 

Gender

   

0.713

  

0.442

Male

46

24

22

 

25

21

 

Female

53

26

27

 

24

29

 

Histology

   

0.523

  

0.718

AC

45

23

22

 

21

24

 

SCC

54

28

26

 

27

27

 

Tumor size

   

0.003*

  

0.001*

T1/T2

46

17

29

 

35

11

 

T3/T4

53

37

16

 

18

35

 

TNM stage

   

0.001*

  

0.000*

I-II

48

10

38

 

36

12

 

III-IV

51

35

16

 

10

41

 

Metastasis

   

0.000*

  

0.000*

Yes

33

27

6

 

4

29

 

No

66

23

43

 

45

21

 
  1. amedian = 0.5115
  2. bmedian = 3.0011
  3. *denotes p value < 0.05
  4. AC: adenocarcinoma; SCC: squamous cell carcinoma; HCC: hepatocellular carcinoma