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Table 3 Principal clinical and pathological features of patients with MMR proteins loss. Fez, Morocco, 2010-2013

From: Epigenetics could explain some Moroccan population colorectal cancers peculiarities: microsatellite instability pathway exploration

Cases Age Gender Localization Histologic type Histologic Differenciation Stage pT Stage pN Stage M Lost proteins
1 45 Male Right colon Adenocarcinoma well 2 0 0 MLH1/PMS2
2 45 Male Right colon Mucinous Carcinoma well 3 0 0 MSH2/MSH6
3 49 Male Rectum Adenocarcinoma well x x 1a MLH1/PMS2
4 80 Female Right colon Adenocarcinoma average 3 0 1a MLH1/PMS2
5 54 Male Left colon Mucinous Carcinoma average 3 0 x MSH2/MSH6
6 64 Female Right colon Adenocarcinoma well 3 0 0 MLH1/PMS2
7 38 Male Right colon Adenocarcinoma well 3 0 x MLH1/PMS2
8 61 Male Right colon Adenocarcinoma well 3 1a x MLH1/PMS2
9 41 Male Left colon Adenocarcinoma well x x 1b MSH2/MSH6
10 55 Male Right colon Adenocarcinoma poor 3 0 x MSH2/MSH6
11 48 Male Right colon Adenocarcinoma poor 4a 0 1b MSH2/MSH6
12 31 Male Rectum Adenocarcinoma average x x 1a MLH1/PMS2
13 71 Male Left colon Adenocarcinoma average 3 2a 1a MLH1/PMS2
14 70 Male Rectum Adenocarcinoma well 3 2a x MLH1/PMS2
15 81 Male Right colon Adenocarcinoma poor 3 0 x MLH1/PMS2
16 50 Female Left colon Adenocarcinoma average x x 1a MLH1/PMS2
17 56 Female Right colon Adenocarcinoma average 4b 0 1b MLH1/PMS2
18 50 Female Right colon Adenocarcinoma average 3 0 1b MLH1/PMS2
19 28 Male Right colon Adenocarcinoma poor 3 0 0 MLH1/PMS2
20 53 Male Right colon Adenocarcinoma well 3 0 0 MSH2/MSH6
21 74 Male Left colon Adenocarcinoma average 3 0 0 MLH1/PMS2
22 53 Male Right colon Adenocarcinoma well 3 0 0 MSH2/MSH6
23 70 Male Not specified Adenocarcinoma well x x x MSH2/MSH6
24 56 Male Left colon Adenocarcinoma well 4b 0 0 MLH1/PMS2