Table 4 Clinicopathological characteristics in CRCs with MMR proteins expression loss/conservation. Fez, Morocco, 2010-2013

Means Age (years)

55.1

56.4

0.7

Age rang < 50 years

8/24

60/190

0.48

Presence of individual or family history of cancer belonging to HNPCC spectrum

4/9

9/190

0.001

0.01

35.8 [95 % CI 2.2- 588]

Well or moderately differentiated adenocarcinoma

15/24

145/190

0.07

Presence of independent cells component

2/24

13/190

0.52

Presence of mucinous component

5/24

33/190

0.43

Presence of perineural invasion

1/19

12/139

0.51

Presence of vascular embolus

4/19

21/139

0.35

Presence of lymph node metastasis

3/19

53/138

0.02

Presence of synchronous colorectal cancer

6/23

5/185

0.0003

Presence of radiological or/and pathological extension to adjacent organs

4/21

16/147

0.22

Presence of visceral metastasis

6/17

31/132

0.21

Presence of peritoneal carcinomatosis

4/20

21/146

0.35

Location

-

-

0.00001

0.02

21 [95 % CI 1.4-316.3]

Right colon

14/23

31/184

-

-

Left colon

6/23

64/184

-

-

Rectum

3/23

89/184

-

-