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Table 1 Characters of reported cases of IVNKL

From: Intravascular NK-cell lymphoma: a case report and review of the literature

Case number/case Age/gender Involved organ(s) Treatment and follow up
1. Santucci et al. [1] 54/M Skin, CNS Chemotherapy, died 17 months after diagnosis
2. Wu et al. [5] 41/M Skin Chemotherapy, alive and event free at 12 months
3. Wu et al. [5] 47/F CNS, bone marrow, kidneys, ovaries, cervix Treatment unclear, died half a month after diagnosis
4. Kuo et al.[6] 71/F Skin Alive 5 months after diagnosis without treatment
5. Song et al. [7] 40/F Skin Chemotherapy, alive and event free at 7 months
6. Nakamichi et al.[8] 23/F Skin Chemotherapy and stem cell transplantation, died of acute GVHD 9 months after diagnosis
7. Cerroni et al. [9] 63/M Skin Chemotherapy, died 6 months after diagnosis
8. Liao et al. [10] 42/F Skin Chemotherapy and radiotherapy, alive with disease 14 months after diagnosis
9. Gebauer et al.[11] 72/M Skin, bone marrow, CNS Chemotherapy, died 7 months after diagnosis
10. Liu et al. [12] 37/F Skin, CNS Chemotherapy, died 13 months after diagnosis
11.our case 29/M Skin, liver Chemotherapy, died 3 months after diagnosis
Case number/case Immunophenotypes PCR-TCR
CD3 CD4 CD5 CD8 CD20 CD30 CD56 Cytotoxic markers EBER
1. Santucci et al. [1] + - NA - - + + + + ND
2. Wu et al. [5] + - - - - - + + + P
3. Wu et al. [5] + - - - - NA + + - P
4. Kuo et al. [6] + - - - - - + + + P
5. Song et al. [7] + - NA - - NA + + + P
6. Nakamichi et al.[8] + NA NA NA - NA + + + ND
7. Cerroni et al. [9] + - NA - - NA + + + P
8. Liao et al.[10] + - - - - - + + + ND
9. Gebauer et al.[11] + - NA - - - + + + P
10. Liu et al. [12] + - - - - - + + + ND
11.our case + - - - - + + + + P
  1. M, male; F, female
  2. GVHD, graft-versus-host disease
  3. NA, not available
  4. cytotoxic markers, TIA-1 and/or granzyme B and/or perforin
  5. PCR-TCR, polymerase chain reaction analysis of the T-cell receptor g gene
  6. P, polyclonal smear