Intravascular NK-cell lymphoma: a case report and review of the literature

Diagnostic Pathology

Table 1 Characters of reported cases of IVNKL

Case number/case	Age/gender	Involved organ(s)	Treatment and follow up
1. Santucci et al. [1]	54/M	Skin, CNS	Chemotherapy, died 17 months after diagnosis
2. Wu et al. [5]	41/M	Skin	Chemotherapy, alive and event free at 12 months
3. Wu et al. [5]	47/F	CNS, bone marrow, kidneys, ovaries, cervix	Treatment unclear, died half a month after diagnosis
4. Kuo et al.[6]	71/F	Skin	Alive 5 months after diagnosis without treatment
5. Song et al. [7]	40/F	Skin	Chemotherapy, alive and event free at 7 months
6. Nakamichi et al.[8]	23/F	Skin	Chemotherapy and stem cell transplantation, died of acute GVHD 9 months after diagnosis
7. Cerroni et al. [9]	63/M	Skin	Chemotherapy, died 6 months after diagnosis
8. Liao et al. [10]	42/F	Skin	Chemotherapy and radiotherapy, alive with disease 14 months after diagnosis
9. Gebauer et al.[11]	72/M	Skin, bone marrow, CNS	Chemotherapy, died 7 months after diagnosis
10. Liu et al. [12]	37/F	Skin, CNS	Chemotherapy, died 13 months after diagnosis
11.our case	29/M	Skin, liver	Chemotherapy, died 3 months after diagnosis
Case number/case	Immunophenotypes									PCR-TCR
Case number/case	CD3	CD4	CD5	CD8	CD20	CD30	CD56	Cytotoxic markers	EBER	PCR-TCR
1. Santucci et al. [1]	+	-	NA	-	-	+	+	+	+	ND
2. Wu et al. [5]	+	-	-	-	-	-	+	+	+	P
3. Wu et al. [5]	+	-	-	-	-	NA	+	+	-	P
4. Kuo et al. [6]	+	-	-	-	-	-	+	+	+	P
5. Song et al. [7]	+	-	NA	-	-	NA	+	+	+	P
6. Nakamichi et al.[8]	+	NA	NA	NA	-	NA	+	+	+	ND
7. Cerroni et al. [9]	+	-	NA	-	-	NA	+	+	+	P
8. Liao et al.[10]	+	-	-	-	-	-	+	+	+	ND
9. Gebauer et al.[11]	+	-	NA	-	-	-	+	+	+	P
10. Liu et al. [12]	+	-	-	-	-	-	+	+	+	ND
11.our case	+	-	-	-	-	+	+	+	+	P

ISSN: 1746-1596