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Table 2 Univariate and multivariate analyses of factors associated with survival and relapse of AML patients

From: Low expression of circulating microRNA-328 is associated with poor prognosis in patients with acute myeloid leukemia

Factors

OS

RFS

Univariate

Multivariate

Univariate

Multivariate

P

Hazard Ratio

95 % CI

P

P

Hazard Ratio

95 % CI

P

Age, years (≤60 vs >60)

0.741

N.A.

N.A.

N.A.

0.675

N.A.

N.A.

N.A.

Gender (male vs female)

0.821

N.A.

N.A.

N.A.

0.514

N.A.

N.A.

N.A.

WBC (<10 vs ≥10, ×109/L)

0.004

1.37

0.67-2.04

0.04

0.009

1.39

0.81-2.33

0.039

HGB (<80 vs ≥80, g/L )

0.009

1.25

0.66-1.79

0.076

0.040

1.120

0.82-1.63

0.247

PLT (<50 vs ≥50, ×109/L)

0.017

1.64

1.07-2.87

0.038

0.274

N.A.

N.A.

N.A.

Blast in BM (<50 % vs ≥50 %)

0.012

1.93

1.09-3.21

0.041

0.213

N.A.

N.A.

N.A.

miR-328 expression (high vs low )

0.009

2.67

1.12-4.73

0.017

0.01

1.914

1.01-3.27

0.023

  1. Abbreviations: WBC white blood cell, HGB hemoglobin, PLT, platelet