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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Paeoniflorin exerts a nephroprotective effect on concanavalin A-induced damage through inhibition of macrophage infiltration

Fig. 1

The hepatorenal protective effect of paeoniflorin (PF) in conA-induced mouse model. a Effect of PF on light micrographic changes in the liver after conA injection (×100). b Effect of PF on serum ALT activity in conA-induced liver injury in mice. c Effect of PF on serum BUN and Cr content. d In conA-induced liver injury in mice, PF (6 mg/kg, 30 mg/kg, and 150 mg/kg) was administered orally 2 h before injection of conA or vehicle for 8 h. The number in HE staining, serum ALT, and renal function was as the same as the animal number in each group. The data represented the mean ± SD # P < 0.05, ## P < 0.01, vs non-conA-vehicle mice, *P < 0.05, * *P < 0.01, vs conA-vehicle mice

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