Fig. 3From: Paeoniflorin exerts a nephroprotective effect on concanavalin A-induced damage through inhibition of macrophage infiltrationEffect of PF on macrophage infiltration and pro-inflammatory cytokines in conA-induced renal damage. a CD68 immunohistochemical staining (×400, n = 3), Brown staining indicates immunopositivity. b real-time PCR showing the change in CD68 (n = 6), (c) IL1β mRNA expression by real-time PCR analysis (n = 6), (d) IL1β content analysis by ELISA analysis, The number in ELISA was as the same as the animal number in each group. e MCP1 mRNA analysis by real-time PCR (n = 6). PF (30 mg/kg) was administered orally 2 h before injection of conA or vehicle for 8 hBack to article page