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Table 2 Cdc7 IHC, clinico-pathological and molecular parameters in CRC

From: Cdc7 overexpression is an independent prognostic marker and a potential therapeutic target in colorectal cancer

   Cdc7
Parameter   Negative (%) Weak (%) Strong (%) p-value
All cancers 1711 33.6 57.2 9.2  
Tumor stage      
pT1 75 25.3 53.3 21.4  
pT2 270 24.1 64.8 11.1  
pT3 1104 34.6 57.5 7.9  
pT4 262 41.6 48.9 9.5 <0.0001
Nodal status      
pN0 889 32.2 58.7 9.1  
pN1 458 36.2 55.0 8.8  
pN2 364 33.8 56.0 10.2 0.5957
Grading      
G1 29 34.5 37.9 27.6  
G2 1505 32.8 58.3 8.9  
G3 177 40.7 50.3 9.0 0.0077
Tumor localization      
Right 414 37.2 53.9 8.9  
Transverse 149 37.6 54.4 8.0  
Left 514 31.6 60.2 8.2  
Rectum 637 30.8 58.3 10.9 0.2093
Histological type      
Tubular 1644 33.5 57.6 8.9  
Mucinous 59 37.3 50.8 11.9 <0.0001
p53      
Negative 530 36.6 53.6 9.8  
Positive 376 25.3 63.0 11.7 0.0013