Table 2 Cdc7 IHC, clinico-pathological and molecular parameters in CRC
| Â | Â | Cdc7 | |||
|---|---|---|---|---|---|
Parameter | Â | Negative (%) | Weak (%) | Strong (%) | p-value |
All cancers | 1711 | 33.6 | 57.2 | 9.2 | Â |
Tumor stage | Â | Â | Â | Â | Â |
pT1 | 75 | 25.3 | 53.3 | 21.4 | Â |
pT2 | 270 | 24.1 | 64.8 | 11.1 | Â |
pT3 | 1104 | 34.6 | 57.5 | 7.9 | Â |
pT4 | 262 | 41.6 | 48.9 | 9.5 | <0.0001 |
Nodal status | Â | Â | Â | Â | Â |
pN0 | 889 | 32.2 | 58.7 | 9.1 | Â |
pN1 | 458 | 36.2 | 55.0 | 8.8 | Â |
pN2 | 364 | 33.8 | 56.0 | 10.2 | 0.5957 |
Grading | Â | Â | Â | Â | Â |
G1 | 29 | 34.5 | 37.9 | 27.6 | Â |
G2 | 1505 | 32.8 | 58.3 | 8.9 | Â |
G3 | 177 | 40.7 | 50.3 | 9.0 | 0.0077 |
Tumor localization | Â | Â | Â | Â | Â |
Right | 414 | 37.2 | 53.9 | 8.9 | Â |
Transverse | 149 | 37.6 | 54.4 | 8.0 | Â |
Left | 514 | 31.6 | 60.2 | 8.2 | Â |
Rectum | 637 | 30.8 | 58.3 | 10.9 | 0.2093 |
Histological type | Â | Â | Â | Â | Â |
Tubular | 1644 | 33.5 | 57.6 | 8.9 | Â |
Mucinous | 59 | 37.3 | 50.8 | 11.9 | <0.0001 |
p53 | Â | Â | Â | Â | Â |
Negative | 530 | 36.6 | 53.6 | 9.8 | Â |
Positive | 376 | 25.3 | 63.0 | 11.7 | 0.0013 |