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Table 2 Detected mutations

From: Detection of KRAS, NRAS and BRAF by mass spectrometry - a sensitive, reliable, fast and cost-effective technique

  

KRAS-LCD Array Kit

Sanger Sequencing

MALDI MS

NGS

KRAS

     

Mutation

 

37

9

46

1

 

A146T

0

4

4

0

 

A146V

0

1

1

0

 

G12A

2

0

2

0

 

G12C

1

0

1

0

 

G12D

16

0

16

0

 

G12R

1

0

1

0

 

G12S

1

0

1

0

 

G12V

11

1

12

1

 

G13D

5

0

5

0

 

Q61H

0

3

3

0

Wild type

 

56

44

44

0

NRAS

     

Mutation

 

2

0

2

0

 

G12D

1

0

1

0

 

G12V

1

0

1

0

Wild type

 

91

53

91

1

BRAF

     

Mutation

 

0

1

1

0

 

V600E

0

1

1

0

Wild type

 

93

52

92

1

Tested Samples

 

93

53

93

1