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Table 5 Associations between rs1019075 and lipid parameters

From: Genetic variants of numb gene were associated with elevated total cholesterol level and low density lipoprotein cholesterol level in Chinese subjects, in Xinjiang, China

 

Mean ± SD

Model 1

Model 2

 

Homozygous for wild allele (C)

Heterozygous

Homozygous for rare allele (T)

P (Dom)

P (Rec)

P (Add)

P (Dom)

P (Rec)

P (Add)

TC (mmol/L)

4.25 ± 1.02

4.30 ± 1.23

4.22 ± 1.10

0.568

0.553

0.331

0.324

0.120

0.029

LDL-C (mmol/L)

2.68 ± 0.90

2.63 ± 0.91

2.57 ± 0.97

0.016

0.008

0.033

0.029

0.007

0.043

HDL-C (mmol/L)

1.02 ± 0.77

1.01 ± 0.46

1.08 ± 0.55

0.022

0.322

0.047

0.031

0.469

0.062

TG (mmol/L)

1.97 ± 1.45

1.95 ± 1.55

2.01 ± 1.47

0.662

0.936

0.719

0.367

0.707

0.353

  1. TC total cholesterol, LDL-C low density lipoprotein-cholesterol, HDL-C high density lipoprotein-cholesterol, TG triglycerides, Dom dominant model, Rec recessive model, Add additive model
  2. Model 1: Unadjusted model; Model 2: Analysis of covariance adjusted for ethnicity, gender, age, smoking and obesity
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Diagnostic Pathology

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