Table 3 Genotype and allele frequencies of IL-8 gene polymorphisms among glioma cases and healthy controls
From: Association between interleukin 8–251 T/A and +781 C/T polymorphisms and glioma risk
Genotypes | Glioma (%) | Controls (%) | OR (95 %CI) | P |
|---|---|---|---|---|
−251 TT | 96 (32.0) | 105 (35.0) | 1.00 (Reference) | |
−251 TA | 120 (40.0) | 147 (49.0) | 0.89 (0.62,1.29) | 0.55 |
−251 AA | 84 (28.0) | 48 (16.0) | 1.91 (1.22,3.00) | 0.005 |
−251 T allele frequency | 312 (52.0) | 357 (59.5) | 1.00 (Reference) | |
−251 A allele frequency | 288 (48.0) | 243 (40.5) | 1.36 (1.08,1.70) | 0.009 |
+781 CC | 166 (55.3) | 161 (53.7) | 1.00 (Reference) | |
+781 CT | 97 (32.3) | 108 (36.0) | 0.87 (0.61,1.24) | 0.44 |
+781 TT | 37 (12.3) | 31 (10.3) | 1.16 (0.69,1.96) | 0.58 |
+781 C allele frequency | 429 (71.5) | 430 (71.7) | 1.00 (Reference) | |
+781 T allele frequency | 171 (28.5) | 170 (28.3) | 1.01 (0.79,1.30) | 0.95 |