Fig. 5

Down-regulation of CRT inhibits the invasive abilities of HCC cells. a. SMMC7721 cells were transfected with CRT siRNA and negative control siRNA for 36 h. The invasive abilities were determined by transwell assay. SMMC7721 without any transfection served as a negative control. SMMC7721 invasive abilities were quantified. Each bar of the histogram represents the number of the invaded cells per high power field. Data are shown as the mean ± SD of at least three independent experiments. b. HepG2 cells were transfected with CRT siRNA and negative control siRNA for 36 h. The invasive abilities were determined by transwell assay. HepG2 without any transfection served as a negative control. HepG2 invasive abilities were quantified. Each bar of the histogram represents the number of the invaded cells per high power field. Data are shown as the mean ± SD of at least three independent experiments. Figures shown are representatives of at least 3 independent experiments. Statistical differences were compared with the siCtrl and NC (*P <0.05)