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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Paraspinal extramedullary hematopoiesis in hereditary spherocytosis with a concurrent follicular lymphoma: case report and review of the literature

Fig. 2

The biopsy of the paravertebral mass showed aggregates of mature hematopoietic tissue, with erythroid islands and normal megakaryocytes consistent with EMH, (a) H&E 40x, (b) H&E 200x. In other areas the tissue was diffusely infiltrated by an atypical lymphoid population of small cells with few large centroblast-like cells, (c) H&E 100x, (d) H&E 400x. The cells are positive for (e) CD20, (f) BCL6 and (g) BCL2. h FISH shows an IGH@/BCL2 translocation in some cells (yellow arrows), (dual color dual fusion probe, x400)

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