Table 5 Clinical specimen results for known KRAS, EGFR and BRAF mutations
KRAS or EGFR or BRAF Mutation Status | ||
|---|---|---|
Sample_ID | Single-Gene Assay | CHP2 Assay |
DNA_01 | EGFR c.2369C > T (p.Thr790Met) | EGFR c.2369C > T (p.Thr790Met) |
DNA_02 | EGFR c.2156G > C p.Gly719Ala | EGFR c.2156G > C p.Gly719Ala |
DNA_03 | Negative | Negative |
DNA_04 | Negative | Negative |
DNA_05 | EGFR Exon 20 INS | EGFR c.2307_2308ins9 (p.V769_D770insASV) |
DNA_06 | Negative | Negative |
DNA_07 | Negative | Negative |
DNA_08 | EGFR c.2369C > T (p.Thr790Met) | EGFR c.2369C > T (p.Thr790Met) |
DNA_09 | EGFR c.2369C > T (p.Thr790Met) | EGFR c.2369C > T (p.Thr790Met) |
DNA_10 | EGFR Exon 19 DEL | EGFR c.2236_2250del15 (p.E746_A750delELREA) |
DNA_11 | Negative | Negative |
DNA_12 | Negative | Negative |
DNA_13 | Negative | Negative |
DNA_14 | Negative | Negative |
DNA_15 | Negative | Negative |
DNA_16 | Negative | Negative |
DNA_17 | Negative | Negative |
DNA_18 | Negative | Negative |
DNA_19 | Negative | Negative |
DNA_20 | Negative | Negative |
DNA_21 | KRAS c.35G > T (p.Gly12Val) | KRAS c.35G > T (p.Gly12Val) |
DNA_22 | Negative | Negative |
DNA_23 | EGFR c.2582 T > A (p.Leu861Gln) | EGFR c.2582 T > A (p.Leu861Gln) |
DNA_24 | EGFR c.2582 T > A (p.Leu861Gln) | EGFR c.2582 T > A (p.Leu861Gln) |
DNA_25 | Negative | Negative |
DNA_26 | BRAF c.1799 T > A (p.Val600Glu) | BRAF c.1799 T > A (p.Val600Glu) |
DNA_27 | KRAS c.34G > A (p.Gly12Ser) | c.34G > A (p.Gly12Ser) |
DNA_28 | Negative | Negative |
DNA_29 | EGFR c.2155G > A (p.Gly719Ser) | EGFR c.2155G > A (p.Gly719Ser) |
DNA_30 | Negative | Negative |
DNA_31 | Negative | Negative |
DNA_32 | KRAS c.34G > T (p.Gly12Cys) | c.34G > T (p.Gly12Cys) |
DNA_33 | BRAF c.1798_1799delGTinsAA (p.Val600Lys) | BRAF c.1798_1799delGTinsAA (p.Val600Lys) |
DNA_34 | BRAF c.1798_1799delGTinsAA (p.Val600Lys) | BRAF c.1798_1799delGTinsAA (p.Val600Lys) |
DNA_35 | EGFR Exon 19 DEL | EGFR c.2235_2246del12 (p.Glu746_Glu749del) |
DNA_36 | Negative | Negative |
DNA_37 | EGFR c.2573 T > G (p.Leu858Arg) | EGFR c.2573 T > G (p.Leu858Arg) |
DNA_38 | EGFR c.2573 T > G (p.Leu858Arg) | EGFR c.2573 T > G (p.Leu858Arg) |
DNA_39 | KRAS c.34G > T (p.Gly12Cys) | c.34G > T (p.Gly12Cys) |
DNA_40 | Negative | Negative |
DNA_41 | KRAS c.38G > A (p.Gly13Asp) | c.38G > A (p.Gly13Asp) |
DNA_42 | KRAS c.38G > A (p.Gly13Asp) | c.38G > A (p.Gly13Asp) |
DNA_43 | EGFR c.2573 T > G (p.Leu858Arg) | Negative |
DNA_44 | EGFR Exon 20 INS | c.2312_2314dupACC (p.Pro772delinsHisPro) |
DNA_45 | Negative | Negative |
DNA_46 | Negative | Negative |
DNA_47 | KRAS c.35G > T (p.Gly12Val) | c.35G > T (p.Gly12Val) |
DNA_48 | Negative | Negative |
DNA_49 | Negative | Negative |
DNA_50 | BRAF c.1799 T > A (p.V600Glu) | c.1799 T > A (p.V600Glu) |
DNA_51 | KRAS c.35G > A (p.Gly12Asp) | c.35G > A (p.Gly12Asp) |
DNA_52 | BRAF c.1799 T > A (p.Val600Glu) | BRAF c.1799 T > A (p.Val600Glu) |
DNA_53 | KRAS c.35G > T (p.Gly12Val) | KRAS c.35G > T (p.Gly12Val) |
DNA_54 | EGFR c.2573 T > G (p.Leu858Arg) | EGFR c.2573 T > G (p.Leu858Arg) |
DNA_55 | BRAF c.1799 T > A (p.Val600Glu) | BRAF c.1799 T > A (p.Val600Glu) |