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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Unusual coexistence of extramedullary plasmacytoma and nasopharyngeal carcinoma in nasopharynx

Fig. 3

Histological and immunohistological features of the second nasopharyngeal biopsy. a. Subepithelial tissue was infiltrated by sheets of a monotonous population consisting of medium-sized atypical plasmacytoid cells without syncytial cell islands. b. immunohistochemical staining showed that the plasmacytoid cells were diffusely positive to CD138 and kappa light chain c, but they were negative to pan-CK (AE1/AE3) (the neighboring epithelium was positive to pan-CK) d, CD20 e and not reactive to EBERs detection f. a, HE staining with original magnification × 400; b-e, immunohistochemical staining with original magnification × 400; f, in situ hybridization for EBERs with original magnification × 400)

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