Table 1 Clinical classification of amyloidosis
Clinical classification of amyloidosis including | |
|---|---|
Systemic amyloidosis | |
Primary systemic amyloidosis(AL> > AH amyloid protein) | |
| Â | Plasma cell dyscrasias (more common) |
| Â | Multiple myeloma-associated |
Secondary systemic amyloidosis (reactive;AA amyloid protein) | |
| Â | Chronic inflammation (e.g.rheumatoid arthritis) |
| Â | Chronic infection (e.g.tuberculosis) |
Heredofamilial amyloidosis (various amyloid proteins) | |
| Â | Familial amyloidotic polyneuropathy |
| Â | Familial Mediterranean fever |
Organ-limited (localized)amyloidosis | |
Cutaneous | |
| Â | Primary:macular, lichen, biphasic, dyschromic, nodular |
| Â | Secondary:within skin tumors |
Endocrine | |
| Â | Medullary carcinoma of the thyroid, insulinoma, type 2 diabetes |
Cerebral | |
| Â | Alzheimer 's disease |