Evaluation of the correlation of KAI1/CD82, CD44, MMP7 and β-catenin in the prediction of prognosis and metastasis in colorectal carcinoma

Table 2 The relationship between expression of KAI1/CD82, CD44, MMP7 and β-catenin and clinicopathogical characteristics of colorectal carcinoma (CRC)

Variables	β-catenin expression		P	KAI1/CD82 expression		P	CD44 expression		P	MMP7 expression		P
Variables	Negative	Positive	P	Negative	Positive	P	Negative	Positive	P	Negative	Positive	P
Sex			0.966			0.871			0.882			0.274
Male	26	75		68	33		39	62		39	62
Female	19	54		50	23		29	44		22	51
Age			0.392			0.531			0.855			0.985
60 years	20	48		48	20		26	42		24	44
≥ 60 years	25	81		70	36		42	64		37	69
Diameter of tumor			0.752			0.861			0.838			0.665
5.0 cm	26	78		70	34		40	64		38	66
≥ 5.0 cm		51			22			42			47
Location			0.164			0.908			0.387			0.182
Rectum	19	70		60	29		32	57		27	62
Colon	26	59		58	27		36	49		34	51
Differentiation			0.731			0.002			0.157			0.852
Well	11	28		18	21		20	19		15	24
Moderate	21	69		63	27		30	60		30	60
Poor	13	32		37	8		18	27		16	29
Depth of invasion			0.449			0.008			0.087			0.694
Under serous membrane	27	69		57	39		43	53		35	61
To serous membrane	18	60		61	17		25	53		26	52
Lymph node metastasis			0.001			<0.001			0.002			0.026
Negative	36	67		58	45		50	53		43	60
Positive	9	62		60	11		18	53		18	53
Distant metastasis			0.009			0.007			0.015			0.042
Negative	44	106		96	54		64	86		57	93
Positive	1	23		22	2		4	20		4	20
TNM stage			0.016			<0.001			<0.001			<0.001
I + II	33	68		52	49		52	49		48	53
III + IV	12	61		66	7		16	57		13	60

ISSN: 1746-1596