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Table 1 Summary of clinico–pathological data and results of thymomas

From: Expression of pRb and p16INK4 in human thymic epithelial tumors in relation to the presence of human polyomavirus 7

Clinicopathological data

HPyV7

P16

ProteinRb

Lab ID

G.

Age

MG

Thym. type

Masaoka–Koga

Anti–AChR

IS/Ster.

IHC 2 t10

 

Anti–Rb

phosRb

1–1

F

73

+

B1/B2

I

+

+

+

+

1–2

F

75

+

B1/B2

I

+

+

+

+

1–11

F

34

+

B2

I

+

++

+

+

1–12

F

36

+

A

I

+

1–16

F

34

+

A

I

+

+

+

+

1–17

M

69

+

AB

I

+

+

(+)

+

+

1–18

F

47

+

AB

I

+

+

(+)

(+)

(+)

1–19

M

68

AB

I

NA

NA

+

+

(+)

(+)

1–21

F

38

+

AB

I

+

+

1–22

M

65

+

AB/B2

I

+

++

(+)

(+)

1–28

M

38

B1

I

NA

NA

(+)

+

+

1–31

F

82

+

A

I

+

+

+

(+)

1–32

M

47

+

B2

I

+

(+)

+

+

1–34

M

59

AB

I

NA

NA

+

+

+

+

1–36

F

82

AB

I

NA

NA

+

+

(+)

(+)

1–39

F

78

B1

I

NA

NA

+

+

+

1–43

F

78

AB

I

NA

NA

(+)

+

+

1–23

M

37

+

AB

IIA

+

+

(+)

+

+

1–24

M

68

+

B2

IIA

+

+

(+)

+

+

1–33

F

43

+

B2

IIA

+

+

(+)

+

1–35

M

45

+

AB

IIA

+

+

+

(+)

1–37

M

77

+

AB

IIA

+

(+)

(+)

+

+

1–38

F

80

+

AB

IIA

+

+

+

1–3

F

57

+

B2/B3

IIB

+

+

(+)

(+)

1–5

M

37

+

B3

IIB

+

+

+

(+)

(+)

1–7

F

79

+

A

IIB

(+)

(+)

(+)

1–8

M

58

+

A/B2

IIB

+

(+)

(+)

(+)

1–9

M

64

B2

IIB

NA

NA

(+)

+

(+)

1–15

F

53

+

B3

IIB

+

+

++

+

+

1–26

M

65

AB

IIB

NA

NA

+

+

1–42

F

57

+

AB

IIB

+

+

+

+

1–10

F

73

+

B3

III

+

+

+

+

1–13

F

54

B2

III

NA

NA

(+)

+

+

+

1–20

M

64

B3

III

NA

NA

+

1–41

M

65

B3

III

NA

NA

+

(+)

+

+

1–4

M

40

+

B2

IVA

+

+

(+)

+

(+)

1–30

M

37

+

B2

IVA

+

+

+

+

        

17/37

19/37

35/37

31/37

46 %

51.4 %

94.6 %

83.8 %

  1. Lab ID laboratory identification, G gender, MG myasthenia gravis, Thym. type thymoma type, anti–AChR anti–acetylcholine receptor antibodies, IS/Ster immunosuppression/steroids, HPyV7 human polyomavirus 7, IHC immunohistochemistry using 2 t10 monoclonal antibody directed against LTag of HPyV7, − negative, (+) weak positive, + positive, ++ strong positive expression, +++ very strong positive expression, NA not applicable
  2. P16 expression – = < 1 %; (+) = 1 %; + = 1–25 %; ++ = > 25 %